Animal Reproduction (AR)
Animal Reproduction (AR)
Original Article

Relationship between Body Mass Index (BMI) and testicular and hormonal parameters of sexually active male greater cane rats (Thryonomys swinderianus)

Adenrele Olalekan Adebayo; Adebayo Kuyoom Akinloye; Bankole Olusiji Oke; Victor Olusegun Taiwo

Downloads: 1
Views: 557


Abstract: The current upsurge in intensive farming practices of greater cane rat has not only lead to higher growth rate but is accompanied by increased fat deposition especially in the males. This study attempts to characterize one of the most commonly used fat estimation parameter, the body mass index (BMI) as well as evaluates its relationship with testicular and hormonal parameters in seventy-two sexually active male cane rats over a period of one year. Six animals, kidded and raised in a farm, with known ages were used each month. The experimental protocols entail body measurements of weight, height and length; histology; orchidometry; and hormonal immunoassay of testosterone, estradiol, progesterone, LH and FSH using their various kits. The mean values of the body mass (BMI) and Lee (LI) indices of male greater cane rats were 1.18±0.20g/cm2 and 0.30±0.02g/cm respectively with the testicular histology indicating normal spermatogenesis. BMI/LI, both of which followed the same pattern, neither correlate with testicular parameters nor with serum testosterone, progesterone, LH and FSH concentrations but had low correlations with serum estradiol concentration (r2 = 0. 2; p = 0.0023). So, these relationships may provide clue on obesity and its effect on reproductive performance and strengthened the possibility of the characterized BMI/LI as obesity marker for breeding selection in male cane rat.


body mass index, hormones, obesity, orchidometry, greater cane rat


Adebayo AO, Oke BO, Akinloye AK. Characterizing the gonadosomatic index and its relationship with age in the greater cane rat (ThryonomysswinderianusTemminck). J Vet Anat. 2009;2(2):53-9.

Adu EK, Otsyina RH, Agyei AD. The efficacy of different dose levels of albendazole for reducing fecal worm egg count in naturally infected captive grasscutter (Thryonomysswinderianus, Temminck). Livest Res Rural Dev. 2005;17:1-6.

Adu EK, Yeboah S. On the use of perineal stain as an index of sexual maturity and breeding condition in the male greater cane rat (Thryonomysswinderianus, Temminck). Trop Anim Health Prod. 2003;35(5):433-9. PMid:14620588.

Aggerholm AS, Thulstrup AM, Toft G, Ramlau-Hansen CH, Bonde JP. Is overweight a risk factor for reduced semen quality and altered serum sex hormone profile? Fertil Steril. 2008;90(3):619-26. PMid:18068160.

Asibey EOA, Addo PG. The grasscutter: a promising animal for meat production. In: Turnham D, editors. African perspectives: practices and policies supporting sustainable development. Harare: Weaver Press; 2000.

ASRM. Obesity and reproduction: a committee opinion. Fertil Steril. 2015;104(5):1116-26. PMid:26434804.

Bahk JY, Jung JH, Jin LM, Min SK. Cut-off value of testes volume in young adults and correlation among testes volume, body mass index, hormonal level, and seminal profiles. Urology. 2010;75(6):1318-23. PMid:20299083.

Eisenberg ML, Kim S, Chen Z, Sundaram R, Schisterman EF, Louis GM. The relationship between male BMI and waist circumference on semen quality: data from the LIFE study. Hum Reprod. 2015;30(2):493-4. PMid:25516559.

Engeland A, Tretli S, Hansen S, Bjorge T. Height and body mass index and risk Lymphohematopoietic Malignancies in two million Norwegian men and women. Am J Epidemiol. 2007;165(1):44-52. PMid:17041129.

German AJ. The growing problems of obesity in dogs and cats. J Nutr. 2006;136(7, Suppl):1940S-6S. PMid:16772464.

Hammiche F, Laven JS, Twigt JM, Boellaard WP, Steegers EA, Steegers-Theunissen RP. Body mass index and central adiposity are associated with sperm quality in men of subfertile couples. Hum Reprod. 2012;27(8):2365-72. PMid:22693175.

Handelsman DJ, Staraj S. Testicular size: the effects of aging, malnutrition, and illness. J Androl. 1985;6(3):144-51. PMid:3997660.

Innocent MC, Asomugha LA, Ukamaka MN, Aronu ME. Ultra-sound measured testicular volume in Nigerian adults: relationship of the three formulae with height, body weight, body-surface area, and body-mass index. International Journal of Advanced Medical and Health Research. 2016;3(2):85-90.

Lu JC, Jing J, Dai JY, Zhao AZ, Yao Q, Fan K, Wang GH, Liang YJ, Chen L, Ge YF, Yao B. Body mass index, waist-to-hip ratio, waist circumference and waist-to-height ratio cannot predict male semen quality: a report of 1231 subfertile Chinese men. Andrologia. 2015;47(9):1047-54. PMid:25418484.

Macdonald AA, Stewart AW, Farquhar CM. Body mass index in relation to semen quality and reproductive hormones in New Zealand men: a cross-sectional study in fertility clinics. Hum Reprod. 2013;28(12):3178-87. PMid:24129611.

Mendeş M, Dinçer E, Arslan E. Profile analysis and growth curve for body mass index of broiler chickens reared under different feed restrictions in early age. Archiv Tierzucht Dummerstorf. 2007;50(4):403-11.

Novelli ELS, Diniz YS, Galhardi CM, Ebaid GMX, Rodrigues HG, Mani F, Fernandes AAH, Cicogna AC, Novelli Filho JLVB. Anthropometrical parameters and markers of obesity in rats. Lab Anim. 2007;41(1):111-9. PMid:17234057.

Opara MN. The grasscutter I: a livestock of tomorrow. Research Journal of Forestry. 2010;4(3):119-35.

Pala A, Savaş T, Uğur F, Daş G. Growth curves of Turkish Saanen Goats’ Kids grouped for weight and body mass index. ArchivTierzuchtDummerstorf. 2005;48(2):185-93.

Papandreou C, Mourad TA, Jildeh C, Abdeen Z, Philalithis A, Tzanakis N. Obesity in Mediterranean region (1997–2007): a systematic review. Obes Rev. 2008;9(5):389-9. PMid:18248588.

Pasquali R, Patton L, Gambineri A. Obesity and infertility. Curr Opin Endocrinol Diabetes Obes. 2007;14(6):482-7. PMid:17982356.

Qin DD, Yuan W, Zhou W, Cui Y, Wu J, Gao E. Do reproductive hormones explain the association between body mass index and semen quality? Asian J Androl. 2007;9(6):827-34. PMid:17968470.

Sakamoto H, Ogawa Y, Yoshida H. Relationship between testicular volume and testicular function: comparison of the Prader orchidometric and ultrasonographic measurements in patients with infertility. Asian J Androl. 2008;10(2):319-24. PMid:18097521.

Spyropoulos E, Borousas D, Mavrikos S, Dellis A, Bourounis M, Athanasiadis S. Size of external genital organs and somatometric parameters among physically normal men younger than 40 years old. Urology. 2002;60(3):485-91. PMid:12350491.

Sobowale OB, Akiwumi O. Testicular volume and seminal fluid profile in fertile and infertile males in Ilorin, Nigeria. Int J Gynaecol Obstet. 1989;28(2):155-61. PMid:2563703.

Wikramanayake E. Testicular size in young adult Sinhalese. Int J Androl. 1995;18(1, Suppl 1):29-31. PMid:7558385.

Zerehdaran S, Vereijken AL, van Arendonk JA, van der Waaijt EH. Estimation of genetic parameters for fat deposition and carcass traits in broilers. Poult Sci. 2004;83(4):521-5. PMid:15109049.

5e4297460e8825f969bf05b1 animreprod Articles
Links & Downloads

Anim Reprod

Share this page
Page Sections