Animal Reproduction (AR)
https://www.animal-reproduction.org/article/doi/10.21451/1984-3143-AR2018-0089
Animal Reproduction (AR)
Conference Paper

Preservation of female fertility in humans and animal species

Helen Mary Picton

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Abstract

A detailed understanding of the cryobiology of gametes and complex tissues has led to the development of methods that facilitate the successful low temperature banking of isolated mature human oocytes, or immature oocytes in situ within fragments of human ovarian cortex. Although many outstanding research challenges remain to be addressed, the successful development of new treatments to preserve female fertility for a range of clinical indications has largely been underpinned by the conduct of extensive, fundamental research on oocytes and ovarian tissues from a number of laboratory and commercially important farm species. Indeed, the most recent evidence from large animals suggests that it is also possible to cryopreserve intact whole ovaries along with their supporting vasculature for later autotransplantation and restoration of natural fertility. This review will explore how the methods developed to preserve human oocytes and ovarian tissues can now be used strategically to support the development of conservation strategies aimed at safeguarding the genetic diversity of commercially important domestic animals and also of preserving the female germplasm for wild animals and endangered species.

Keywords

cryopreservation, fertility preservation, oocyte, ovary.

References

Almodin CG, Minguetti-Camara VC, Meister H, Ferreira JO, Franco RL, Cavalcante AA, Radaelli MR, Bahls AS, Moron AF, Murta CG. 2004. Recovery of fertility after grafting of cryopreserved germinative tissue in female rabbitsfollowing radiotherapy. Hum Reprod, 19:1287-1293.

Andrabi SM, Maxwell WM. 2007. A review on reproductive biotechnologies for conservation of endangered mammalian species. Anim Reprod Sci, 99:223-243.

Baird DT, Webb R, Campbell BK, Harkness LM, Gosden RG. 1999. Long-term ovarian function in sheep after ovariectomy and transplantation of autografts stored at -196 C. Endocrinology, 140:462-471.

Baudot A, Courbiere B, Odagescu V, Salle B, Mazoyer C, Massardier J, Lornage J. 2007. Towards whole sheep ovary cryopreservation. Cryobiology, 55:236-248.

Bordes A, Lornage J, Demirci B, Franck M, Courbiere B, Guerin JF, Salle B. 2005. Normal gestations and live births after ortho-topic autograft of vitrified-warmed hemi-ovaries into ewes. Hum Reprod, 20:2745-2748.

Bosch P, Hernandez-Fonseca HJ, Miller DM, Wininger JD, Massey JB, Lamb SV, Brackett BG. 2004. Development of antral follicles in cryopreserved cat ovarian tissue transplanted to immunodeficient mice. Theriogenology, 61:581-594.

Boutelle S, LenahanK, Krisher R, Bauman KL, Asa CS, Silber S. 2011. Vitrification ofoocytes from endangered Mexican gray wolves (Canis lupus baileyi). Theriogenology, 75:647-654.

Campbell BK, Hernandez-Medrano J, Onions V, Pincott-Allen C, Aljaser F, Fisher J, McNeilly AS, Webb R, Picton HM. 2014. Restoration of ovarian function and natural fertility following the cryopreservation and autotransplantation of whole adult sheep ovaries. Hum Reprod, 29:1749-1763.

Candy CJ, Wood MJ, Whittingham DG. 1995. Follicular development in cryopreserved marmoset ovarian tissue after transplantation. Hum Reprod, 10:2334-2338.

Carvalho AA, Faustino LR, Silva CM, Castro SV, Lopes CA, Santos RR, Báo SN, Figueiredo JR, Rodrigues AP. 2013 Novel wide-capacity method for vitrification of caprine ovaries: ovarian tissue cryosystem (OTC). Anim Reprod Sci, 138:220-227.

Chambers EL, Gosden RG, Yap C, Picton HM. 2010. In situ identification of follicles in ovarian cortex as a tool for quantifying follicle density, viability and developmental potential in strategies to preserve female fertility. Hum Reprod, 25:2559-2568.

Cleary M, Paris MCJ, Shaw J, Jenkin G, Trounson A. 2003. Effect of ovariectomy and graft position on cryopreserved commonwombat (Vombatus ursinus) ovarian tissue following xenografting to nude mice. Reprod Fertil Dev, 15:333-334.

Cobo A, García-Velasco JA. 2016. Why all women should freeze their eggs. Curr Opin Obstet Gynecol, 28:206-210.

Comizzzoli P, Wildt DE, Pukazhenti BS. 2008. Impact of anisosmotic conditions on structural integrity of cumulus-oocyte complexes at the germinal vesicle stage in the domestic cat. Mol Reprod Dev, 75:345-354.

Comizzoli P, Crosier AE, Songsasen N, Gunther MS, Howard JG, Wildt DE. 2009. Advances in reproductive science for wild carnivore conservation. Reprod Domest Anim, 44(suppl. 2):47-52.

Comizzoli P, Songsasen N, Wildt DE. 2010. Protecting and extending fertility for females of wild and endangered mammals. Cancer Treat Res, 156:87- 100.

Comizzoli P, Songsasen N, Hagedorn M, Wildt DE. 2012. Comparitive cryobiological traits and requirements for gametes and gonadal tissues collected from wildlife species. Theriogenology, 78:1666-1681.

Comizzoli P, Wildt DE. 2012. On the horizon for fertility preservation in domestic and wild carnivores. Reprod Domest Anim, 47(suppl. 6):261-285.

Comizzoli P. 2017. Biobanking and fertility preservation for rare and endangered species. Anim Reprod, 14:30-33.

Czarny NA, Roger JC. 2010. Vitrification as a method forgenome resource banking from the endangered Tasmanian devil (Sarcophilus harrisii). Cryobiology, 60:322-325

Demeestere I, Simon P, Dedeken L, Moffa F, Tsépélidis S, Brachet C, Delbaere A, Devreker F, Ferster A. 2015. Live birth after autograft of ovarian tissue cryopreserved during childhood. Hum Reprod, 30:2107-2109.

Devi L, Goel S. 2016. Fertility preservation through gonadal cryopreservation. Reprod Mol Biol, 15:235- 251.

Dolmans MM, Masciangelo R. 2018. Risk of transplanting malignant cells in cryopreserved ovarian tissue. Minerva Ginecol, 70:436-443.

Ehmcke J, Schlatt S. 2008. Animal models for fertility preservation in the male. Reproduction, 136:717-723 Eppig JJ, O'Brien MJ. 1996. Development in vitro of mouse oocytes from primordial follicles. Biol Reprod, 54:197-207

Fernandez-Gonzalez L, Jewgenow K. 2017. Cryopreservation of feline oocytes by vitrification using commercial kits and slush nitrogen technique. Reprod Domest Anim, 52(suppl. 2):230-234

Gandolfi F, Paffoni A, Papasso Brambilla E, Bonetti S, Brevini TA, Ragni G. 2006. Efficiency of equilibrium cooling and vitrification procedures for the cryopreservation of ovarian tissue: comparative analysis between human and animal models. Fertil Steril, 85(suppl. 1):1150-1156

Gellert SE, Pors SE, Kristensen SG, Bay-Bjørn AM, Ernst E2,, Yding Andersen C. 2018. Transplantation of frozen-thawed ovarian tissue: an update on worldwide activity published in peer-reviewed papers and on the Danish cohort. J Assist Reprod Genet, 35:561-570.

Glujovsky D, Riestra B, Sueldo C, Fiszbajn G, Repping S, Nodar F, Papier S, Ciapponi A. 2014. Vitrification versus slow freezing for women undergoing oocyte cryopreservation. Cochrane Database Syst Rev, (9):CD010047. doi:10.1002/14651858.CD010047.

Goldman RH, Racowsky C, Farland LV, Munné S, Ribustello L, Fox JH. 2017. Predicting the likelihood of live birth for elective oocyte cryopreservation: a counseling tool for physicians and patients. Hum Reprod, 32:853-859.

Gosden RG, Baird DT, Wade JC, Webb R. 1994. Restoration of fertility to oophorectomized sheep by ovarian autografts stored at -196 degrees C. Hum Reprod, 9:597-603.

Gunasena KT, Lakey JR, Villines PM, Bush M, Raath C, Critser ES, McGann LE, Critser JK. 1998. Antral follicles develop in xenografted cryopreserved African elephant (Loxodonta africana) ovarian tissue. Anim Reprod Sci, 53:265-275.

Harp R, Leibach J, Black J, Keldahl C, Karow A. 1994. Cryopreservation of murine ovarian tissue. Cryobiology, 31:336-343.

Hayashi K, Hikabe O, Obata Y, Hirao Y. 2017. Reconstitution of mouse oogenesis in a dish from pluripotent stem cells. Nat Protoc, 12:1733-1744.

Hikabe O, Hamazaki N, Nagamatsu G, Obata Y, Hirao Y, Hamada N, Shimamoto S, Imamura T, Nakashima K, Saitou M, Hayashi K. 2016. Reconstitution in vitro of the entire cycle of the mouse female germ line. Nature, 539:299-303.

Howard JG, Wildt DE. 2009. Approaches and efficacy of artificial insemination in felids and mustelids. Theriogenology, 71:130-148.

Huang Y, Li D, Zhou Y, Zhou Q, Li R, Wang C, Huang Z, Hull V, Zhang H. 2012. Factors affecting the outcome of artificial insemination using cryopreserved spermatozoa in the giant panda (Ailuropoda melanoleuca). Zoo Biol, 31:561-173 Ishijima T, Kobayashi Y, Lee DS, Ueta YY, Matsui M, Lee JY, Miyahara K, Suzuki H. 2006. Cryopreservation of canine ovaries by vitrification. J Reprod Dev, 52:293-299.

Jadoul P, Guilmain A, Squifflet J, Luyckx M, Votino R, Wyns C, Dolmans MM. 2017. Efficacy of ovarian tissue cryopreservation for fertility preservation: lessons learned from 545 cases. Hum Reprod, 32:1046-1054.

Kagawa N, Silber S, Kuwayama M. 2009. Successful vitrification of bovine and human ovarian tissue. Reprod Biomed Online, 18:568-577.

Kedem A, Yerushalmi GM, Brengauz M, Raanani H, Orvieto R, Hourvitz A, Meirow D. 2018. Outcome of immature oocytes collection of 119 cancer patients during ovarian tissue harvesting for fertility preservation. J Assist Reprod Genet, 35:851-856.

Kim SS, Radford J, Harris M, Varley J, Rutherford AJ, Lieberman B, Shalet S, Gosden R. 2001. Ovarian tissue harvested from lymphoma patients to preserve fertility may be safe for autotransplantation. Hum Reprod, 16:2056-2060

Kim SS, Kang HG, Kim NH, Lee HC, Lee HH. 2005. Assessment of the integrity of human oocytes retrieved from cryopreserved ovarian tissue after xenotransplantation. Hum Reprod, 20:2502-2508.

Leibo SP, Songsasen N. 2002. Cryopreservation of gametes and embryos of non-domestic species. Theriogenology, 57:303-326.

Luvoni GC. 2006. Gamete cryopreservation in the domestic cat. Theriogenology, 66:101-111. Madboly MM, Abdel-Aal ES, Elsayed EH. 2017. Impact of cryopreservation method on dromedary camel ovary structure, viability, and development of antral follicular oocytes. Anim Reprod Sci, 184:120-131.

Martinez-Madrid B, Dolmans MM, Van Langendonckt A, Defrère S, Donnez J. 2004. Freezethawing intact human ovary with its vascular pedicle with a passive cooling device. Fertil Steril, 82:1390- 1394.

Matthews SJ, Picton HM, Ernst E, Andersen CY. 2018. Successful pregnancy in a woman previously suffering from β-thalassaemia following transplantation of ovarian tissue cryopreserved before puberty. Minerva Ginecol, 70:432-435.

Mattiske D, Shaw G. Shaw J.M. 2002. Infuence of donor age on development of gonadal tissue from pouch young of the tammar wallaby, Macropus eugenii , after cryopreservation and xenografting into mice. Reproduction, 123:143-153

Migishima F, Suzuki-Migishima R, Song SY, Kuramochi T, Azuma S, Nishijima M, Yokoyama M. 2003. Successful cryopreservation of mouse ovaries by vitrification. Biol Reprod, 68:881-887.

Mullen SF, Agca Y, Broermann DC, Jenkins CL, Johnson CA, Critser JK. 2004. The effect of osmotic stress on the metaphase II spindle of human oocytes, and the relevance to cryopreservation. Hum Reprod, 19:1148-1154.

Newton H, Aubard Y, Rutherford A, Sharma V, Gosden R. 1996. Low temperature storage and grafting of human ovarian tissue. Hum Reprod, 11:1487-1491.

Newton H, Fisher J, Arnold JR, Pegg DE, Faddy MJ, Gosden RG. 1998. Permeation of human ovarian tissue with cryoprotective agents in preparation for cryopreservation. Hum Reprod, 13:376-380.

Newton H, Picton HM, Gosden RG. 1999. In vitro growth of preantral follicles isolated from frozen/thawed ovine tissue. J Reprod Fertil, 115:141-150.

Oktay K, Newton H, Mullan J, Gosden RG. 1998. Development of human primordial follicles to antral stages in SCID/hpg mice stimulated with follicle stimulating hormone. Hum Reprod, 13:1133-1138.

Oktay K, Cil AP, Bang H. 2006. Efficiency of oocyte cryopreservation: a meta-analysis. Fertil Steril, 86:70- 80.

Oktay K, Bedoschi G, Berkowitz K, Bronson R, Kashani B, McGovern P, Pal L, Quinn G, Rubin K. 2016. Fertility preservation in women with turner syndrome: a comprehensive review and practical guidelines. J Pediatr Adolesc Gynecol, 29:409-416.

Oktay K, Harvey BE, Partridge AH, Quinn GP, Reinecke J, Taylor HS, Wallace WH, Wang ET, Loren AW. 2018. Fertility preservation in patients with cancer: ASCO clinical practice guideline update. J Clin Oncol, 36:1994-2001.

Onions VJ, Webb R, McNeilly AS, Campbell BK. 2009. Ovarian endocrine profile and long-term vascular patency following heterotopic autotransplantation of cryopreserved whole ovine ovaries. Hum Reprod, 24:2845-2855.

Onions VJ, Webb R, Pincott-Allen C, Picton HM, Campbell BK. 2013. The effects of whole ovarian perfusion and cryopreservation on endothelial cellrelated gene expression in the ovarian medulla and pedicle. Mol Hum Reprod, 19:205-215.

Ortiz-Escribano N, Bogado Pascottini O, Woelders H, Vandenberghe L, De Schauwer C, Govaere J, Van den Abbeel E, Vullers T, Ververs C, Roels K, Van De Velde M, Van Soom A, Smits K. 2018. An improved vitrification protocol for equine immature oocytes, resulting in a first live foal. Equine Vet J, 50:391-397.

Pacheco F, Oktay K. 2017. Current success and efficiency of autologous ovarian transplantation: a metaanalysis. Reprod Sci, 24:1111-1120.

Parrott DMV. 1960. The fertility of mice with orthotopic ovarian grafts derived from frozen tissue. J Reprod Fertil, 1:230-241.

Paulson RJ, Comizzoli P. 2018. Addressing challenges in developing and implementing successful in vitro fertilization in endangered species: an opportunity for humanity to "give back". Fertil Steril, 109:418-419.

Pickering SJ, Johnson MH. 1987. The influence of cooling on the organization of the meiotic spindle of the mouse oocyte. Hum Reprod, 2:207-216.

Pickering SJ, Braude PR, Johnson MH, Cant A, Currie J. 1990. Transient cooling to room temperature can cause irreversible disruption of the meiotic spindle in the human oocyte. Fertil Steril, 54:102-108.

Picton HM, Kim S, Gosden RG. 2000. Cryopreservation of gonadal tissue and cells. Br Med Bull, 56:603-615.

Picton HM. 2001. Activation of follicle development: the primordial follicle. Theriogenology, 55:1193-1210.

Picton HM, Danfour MA, Harris SE, Chambers EL, Huntriss J. 2003. Growth and maturation of oocytes in vitro. Reprod Suppl, 61:445-462.

Picton HM, Harris SE, Muruvi W, Chambers EL. 2008. The in vitro growth and maturation of follicles. Reproduction, 136:703-715.

Picton H, Chambers E. 2009. Egg freezing: the reality and practicality. In: Bewley S, Ledger W, Nikolaou D (Ed.). Reproductive Ageing. London: Cambridge University Press. pp. 211-226.

Picton HM, Wyns C, Anderson RA, Goossens E, Jahnukainen K, Kliesch S, Mitchell RT, Pennings G, Rives N, Tournaye H, Van Pelt AMM, EichenlaubRitter U, Vanden Abbeel E, Schlatt S. 2015. A European perspective on testicular tissue cryopreservation for fertility preservation in prepubertal and adolescent boys. Hum Reprod, 11:2463-2475.

Rahimi G, Isachenko E, Isachenko V, Sauer H, Wartenberg M, Tawadros S, Hescheler J, Mallmann P, Nawroth F. 2004. Comparison of necrosis in human ovariantissue after conventional slow freezing or vitrification and transplantation in ovariectomized SCID mice. Reprod Biomed Online, 9:187-193

Rienzi L, Gracia C, Maggiulli R, LaBarbera AR, Kaser DJ, Ubaldi FM, Vanderpoel S, Racowsky C. 2017. Oocyte, embryo and blastocyst cryopreservation in ART: systematic review and meta-analysis comparing slow-freezing versus vitrification to produce evidence for the development of global guidance. Hum Reprod Update, 23:139-155.

Santana LN, Van den Hurk R, Oskam IC, Brito AB, Brito DC, Domingues SF, Santos RR. 2012. Vitrification of ovarian tissue from primates and domestic ruminants: an overview. Biopreserv Biobank, 10:288-294.

Santos RR, Tharasanit T, Van Haeften T, Figueiredo JR, Silva JR, Van den Hurk R. 2007. Vitrification of goat preantral follicles enclosed in ovarian tissue by using conventional and solid-surface vitrification methods. Cell Tissue Res, 327:167-176.

Saragusty J, Arav A. 2011. Current progress in oocyte and embryo cryopreservation by slow freezing and vitrification. Reproduction, 141:1-19. doi: 10.1530/REP-10-0236.

Silva RC, Costa GM, Lacerda SM, Batlouni SR, Soares JM, Avelar GF, Böttger KB, Silva SF Jr, Nogueira MS, Andrade LM, França LR. 2012. Germ cell transplantation in felids: a potential approach to preserving endangered species. J Androl, 33:264-276.

Snow M, Cox SL, Jenkin G, Trounson A, Shaw J. 2002. Generation of live young from xenografted mouse ovaries. Science, 297:2227.

Songsasen N, Ratterree MS, VandeVoort CA, Pegg DE, Leibo SP. 2002. Permeability characteristics and osmotic sensitivity of rhesus monkey (Macaca mulatta) oocytes. Hum Reprod, 17:1875-1884.

Suzuki N, Yoshioka N, Takae S, Sugishita Y, Tamura M, Hashimoto S, Morimoto Y, Kawamura K. 2015. Successful fertility preservation following ovarian tissue vitrification in patients with primary ovarian insufficiency. Hum Reprod, 30:608-615.

Taberlet P, Valentini A, Rezaei HR, Naderi S, Pompanon F, Negrini R, Ajmone-Marsan P. 2008. Are cattle, sheep, and goats endangered species? Mol Ecol, 17:275-284.

Tokieda Y, Ishiwata I, Segino M, Ishikawa H, Sato K. 2002. Establishment of a novel method for cryopreservation and thawing of the mouse ovary. Hum Cell, 15:230-237.

Wang X, Chen H, Yin H, Kim SS, Lin Tan S, Gosden RG. 2002. Fertility after intact ovary transplantation. Nature, 415:385.

Whittingham DG, Leibo SP, Mazur P. 1972. Survival of mouse embryos frozen to -196 degrees and -269 degrees C. Science, 178:411-414.

Wiedemann C, Hribal R, Ringleb J, Bertelsen MF, Rasmusen K, Andersen CY, Kristensen SG, Jewgenow K. 2012. Preservation of primordial follicles from lions by slow freezing and xenotransplantation of ovarian cortex into an immunodeficient mouse. Reprod Domest Anim, 47(suppl. 6):300-304.

Wildt DE, Comizzoli P, Pukazhenthi B, Songsasen N. 2010. Lessons from biodiversity- the value of nontraditional species to advance reproductive science, conservation, and human health. Mol Reprod Dev, 77:397-409.

Woods EJ, Benson JD, Agea Y, Critser JK. 2004. Fundamental cryobiology of reproductive cells and tissues. Cryobiology, 48:146-156.

Xu M, Fazleabas AT, Shikanov A, Jackson E, Barrett SL, Hirshfeld-Cytron J, Kiesewetter SE, Shea LD, Woodruff TK. 2011. In vitro oocyte maturation and preantral follicle culture from the lutealphase baboon ovary produce mature oocytes. Biol Reprod, 84:689-697.

Zenzes MT, Bielecki R, Casper RF, Leibo SP. 2001. Effects of chilling to 0 degrees C on the morphology of meiotic spindles in human metaphase II oocytes. Fertil Steril, 75:769-777.

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